Concepedia

Memantine Induces NMDAR1-Mediated Autophagic Cell Death in Malignant Glioma Cells

Wan‐Soo Yoon, Mi-Young Yeom, Eun-Sun Kang, Yong‐An Chung, Dong‐Sup Chung, Sin‐Soo Jeun

Journal of Korean Neurosurgical Society · 2017 · 32 citations · 25 references

DOIFull text

Open access

Abstract

Our study demonstrates that in glioma cells, memantine inhibits proliferation and induces autophagy mediated by NMDAR1.

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