PKC-epsilon and TLR4 synergistically regulate resistin-mediated inflammation in human macrophages

The hormone resistin links obesity to diabetes

Claire M. Steppan, Shannon T. Bailey, Savitha Bhat et al. · Nature · 2001 · 4.7K citations

Insulin Resistance, Metabolic Syndrome, Obesity +10

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

Thomas Vogl, Klaus Tenbrock, Stephan Ludwig et al. · Nature Medicine · 2007 · 1.4K citations

Inflammation, Toll-like Receptors, Molecular Immunology +13

PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties

Mohamed Amine Bouhlel, Bruno Derudas, Elena Rigamonti et al. · Cell Metabolism · 2007 · 1.3K citations · Full text

Inflammation, Macrophage Biology, Cytokine +11

Resistin, an Adipokine with Potent Proinflammatory Properties

Maria Bokarewa, Ivan Nagaev, Leif Dahlberg et al. · The Journal of Immunology · 2005 · 1K citations

Reduction of atherosclerosis in mice by inhibition of CD40 signalling

François Mach, Uwe Schönbeck, Galina K. Sukhova et al. · Nature · 1998 · 912 citations

Inflammation, Vascular Disease, Atherosclerosis +7