Concepedia

Involvement of pregnane X receptor in the suppression of carboxylesterases by metformin in vivo and in vitro, mediated by the activation of AMPK and JNK signaling pathway

Enfang Shan, Zhu Zhu, Shuangcheng He, Dongbao Chu, Dinghao Ge, Yunran Zhan, Wei Liu, Jian Yang, Jing Xiong

European Journal of Pharmaceutical Sciences · 2017 · 13 citations · 33 references

DOI

Concepts

References

33

Dose translation from animal to human studies revisited

Shannon Reagan‐Shaw, Minakshi Nihal, Nihal Ahmad · The FASEB Journal · 2007 · 6.3K citations

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Role of NF-κB in Regulation of PXR-mediated Gene Expression

Xinsheng Gu, Sui Ke, Duan Liu et al. · Journal of Biological Chemistry · 2006 · 301 citations · Full text

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Anti-Influenza Prodrug Oseltamivir Is Activated by Carboxylesterase Human Carboxylesterase 1, and the Activation Is Inhibited by Antiplatelet Agent Clopidogrel

Deshi Shi, Jian Yang, Dongfang Yang et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 277 citations · Full text

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Antiplatelet Agents Aspirin and Clopidogrel Are Hydrolyzed by Distinct Carboxylesterases, and Clopidogrel Is Transesterificated in the Presence of Ethyl Alcohol

Man Tang, Madhu Mukundan, Jian Yang et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 250 citations

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Resveratrol ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice

Heng Zhang, Zhibin Zhai, Yueying Wang et al. · Free Radical Biology and Medicine · 2012 · 207 citations

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