The role of autophagy in neurodegenerative disease

Ralph A. Nixon

Nature Medicine

Cell AutophagyNeurodegenerative DiseasesMitophagyAutophagyCell Death +7

Network organization of the human autophagy system

Christian Behrends, Mathew E. Sowa, Steven P. Gygi, +1

Nature

Cell AutophagyMitophagyNetwork ScienceEngineeringBiological Network +8

The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy

Takao Hanada, Nobuo N. Noda, Yoshinori Satomi, +5

Journal of Biological Chemistry

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

Naonobu Fujita, Takashi Itoh, Hiroko Omori, +3

Molecular Biology of the Cell

Cell AutophagyMitophagyLc3 LipidationMembrane BiogenesisBiochemistry +10

The Atg5–Atg12 conjugate associates with innate antiviral immune responses

Nao Jounai, Fumihiko Takeshita, Kouji Kobiyama, +8

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyViral PathogenesisImmunologic MechanismInnate Immunity +14

A New Protein Conjugation System in Human

Noboru Mizushima, Hisao Sugita, Tamotsu Yoshimori, +1

Journal of Biological Chemistry

Mechanism and functions of membrane binding by the Atg5–Atg12/Atg16 complex during autophagosome formation

Julia Romanov, Marta Walczak, Iosune Ibiricu, +4

The EMBO Journal

FoxO Transcription Factors Promote Autophagy in Cardiomyocytes

Arunima Sengupta, Jeffery D. Molkentin, Katherine E. Yutzey

Journal of Biological Chemistry

Cell AutophagyMitophagyTranscriptional RegulationCell SizeCardiomyopathy +13

Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia

Huiyu Liu, Jianmin Han, Sophia Y. Cao, +5

Journal of Biological Chemistry

The Autophagy Protein Atg12 Associates with Antiapoptotic Bcl-2 Family Members to Promote Mitochondrial Apoptosis

Assaf D. Rubinstein, Miriam Eisenstein, Yaara Ber, +2

Molecular Cell

Cell AutophagyMitophagyMitochondrial ApoptosisMitochondrial FunctionApoptosis +7