The Atg5–Atg12 conjugate associates with innate antiviral immune responses

Nao Jounai, Fumihiko Takeshita, Kouji Kobiyama, +8

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyViral PathogenesisImmunologic MechanismInnate Immunity +14

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry

Holger Winkels, Erik Ehinger, Melanie Vassallo, +17

Circulation Research

DNA released from dying host cells mediates aluminum adjuvant activity

Thomas Marichal, Keiichi Ohata, Denis Bedoret, +9

Nature Medicine

Natural SciencesCell DeathDna ReplicationMolecular BiologyAluminum Adjuvant Activity +3

Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike

Daichi Yamasoba, Izumi Kimura, Hesham Nasser, +47

Cell

VaccinationGlobal SpreadBa.2 Spike-bearing VirusViral PersistenceVaccine Development +12

DNA-Containing Exosomes Derived from Cancer Cells Treated with Topotecan Activate a STING-Dependent Pathway and Reinforce Antitumor Immunity

Yuichi Kitai, Takumi Kawasaki, Takuya Sueyoshi, +6

The Journal of Immunology

Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5

Izumi Kimura, Daichi Yamasoba, Tomokazu Tamura, +41

Cell

Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production

Marco Orecchioni, Kouji Kobiyama, Holger Winkels, +26

Science

NLRP4 Negatively Regulates Autophagic Processes through an Association with Beclin1

Nao Jounai, Kouji Kobiyama, Masaaki Shiina, +3

The Journal of Immunology

Innate Immune SystemImmunologyCell DeathInflammationCell Autophagy +14

Regulatory CD4 ⁺ T Cells Recognize Major Histocompatibility Complex Class II Molecule–Restricted Peptide Epitopes of Apolipoprotein B

Takayuki Kimura, Kouji Kobiyama, Holger Winkels, +22

Circulation

Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B ₁₀₀ –Reactive CD4 ⁺ T-Regulatory Cells

Dennis Wolf, Teresa Gerhardt, Holger Winkels, +30

Circulation