PSCA and MUC1 in non-small-cell lung cancer as targets of chimeric antigen receptor T cells

Abstract

tumors when combined with MUC1-targeting CAR T cells. Taken together, our studies demonstrate that PSCA and MUC1 are both promising CAR T cell targets in NSCLC and that the combinatorial targeting of these antigens could further enhance the antitumor efficacy of CAR T cells.