Imaging Characteristics of Pediatric Diffuse Midline Gliomas with Histone H3 K27M Mutation

Abstract

We describe, for the first time, the MR imaging features of pediatric diffuse midline gliomas with histone H3 K27M mutation. Similar to the heterogeneous histologic features among these tumors, they also have a diverse imaging appearance without distinguishing features from histone H3 wildtype diffuse gliomas.