Dregamine and tabernaemontanine derivatives as ABCB1 modulators on resistant cancer cells

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

Ting‐Chao Chou · Cancer Research · 2010 · 5.7K citations

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A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells.

Ira Pastan, Michael M. Gottesman, Kazumitsu Ueda et al. · Proceedings of the National Academy of Sciences · 1988 · 491 citations · Full text

Life Sciences, Microbiology, Pharmacology +11

Essential features of the P-glycoprotein pharmacophore as defined by a series of reserpine analogs that modulate multidrug resistance.

Homer L. Pearce, Ahmad R. Safa, Nicholas J. Bach et al. · Proceedings of the National Academy of Sciences · 1989 · 234 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

The effect of ion channel blockers, immunosuppressive agents, and other drugs on the activity of the multi‐drug transporter

James L. Weaver, P. Scott Pine, Adorján Aszalós et al. · International Journal of Cancer · 1993 · 92 citations · Full text

Medicine, Oncology, Pharmacology +16

Cytotoxicity of the indole alkaloid reserpine from Rauwolfia serpentina against drug-resistant tumor cells

Sara Abdelfatah, Thomas Efferth · Phytomedicine · 2015 · 82 citations

Medicine, Oncology, Pharmacology +8