The promising anticancer drug 3-bromopyruvate is metabolized through glutathione conjugation which affects chemoresistance and clinical practice: An evidence-based view

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

Chang-jie Chen, Janice E. Chin, Kazumitsu Ueda et al. · Cell · 1986 · 1.9K citations

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ACETAMINOPHEN-INDUCED HEPATIC NECROSIS. IV. PROTECTIVE ROLE OF GLUTATHIONE

J.R. Mitchell, David J. Jollow, William Z. Potter et al. · Journal of Pharmacology and Experimental Therapeutics · 1973 · 1.7K citations

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Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs.

Angelo Russo, William DeGraff, Norman R. Friedman et al. · PubMed · 1986 · 386 citations

Medicine, Oncology, Pharmacology +16

Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP

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Medicine, Cancer Biology, Oncology +12

Nucleotide sequence and the encoded amino acids of human serum albumin mRNA.

Achilles Dugaiczyk, S W Law, Olivia Dennison · Proceedings of the National Academy of Sciences · 1982 · 318 citations

Life Sciences, Biochemistry, Molecular Biology +14