Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS

Valentina Pirro, Alan K. Jarmusch, Clint M. Alfaro, Eyas M. Hattab, Aaron Cohen‐Gadol, R. Graham Cooks

The Analyst · 2017 · 37 citations · 18 references

Concepts

Abstract

Analysis of neurological smears by desorption electrospray ionization mass spectrometry (DESI-MS) is an emerging diagnostic strategy for intraoperative consultation in brain tumor resection. DESI-MS allows rapid sampling while providing accurate diagnostic information. We assess the chemical homogeneity of neurological smears using DESI-MS imaging and the quality of rapid DESI-MS diagnosis.

References

18