Concepedia

Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels

Alessandro Carrer, Joshua L.D. Parris, Sophie Trefely, Ryan A. Henry, David C. Montgomery, AnnMarie Torres, John M. Viola, Yin‐Ming Kuo, Ian A. Blair, Jordan L. Meier,

Journal of Biological Chemistry · 2017 · 158 citations · 32 references

DOIFull text

Open access

Concepts

Abstract

This study thus provides evidence that diet can impact tissue acyl-CoA and histone acetylation levels and that acetyl-CoA abundance correlates with acetylation of specific histone lysines in WAT but not in the liver.

References

32

ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

Kathryn E. Wellen, Georgia Hatzivassiliou, Uma M. Sachdeva et al. · Science · 2009 · 2.2K citations · Full text

, , +14

Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

Tadahiro Shimazu, Matthew D. Hirschey, Wenjuan He et al. · Science · 2012 · 1.7K citations · Full text

, , +17

National, regional, and global trends in adult overweight and obesity prevalences

Gretchen A Stevens, Gitanjali M Singh, Yuan Lu et al. · Population Health Metrics · 2012 · 929 citations · Full text

, , +12

The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation

Dallas R. Donohoe, Leonard B. Collins, Aminah Wali et al. · Molecular Cell · 2012 · 927 citations · Full text

, , +16

Distinct roles of GCN5/PCAF‐mediated H3K9ac and CBP/p300‐mediated H3K18/27ac in nuclear receptor transactivation

Qihuang Jin, Li‐Rong Yu, Lifeng Wang et al. · The EMBO Journal · 2010 · 905 citations · Full text

, , +9