The Bacterial T6SS Effector EvpP Prevents NLRP3 Inflammasome Activation by Inhibiting the Ca2+-Dependent MAPK-Jnk Pathway

The Inflammasome

Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell · 2002 · 5.9K citations · Full text

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung, Franz Bauernfeind, Annett Halle et al. · Nature Immunology · 2008 · 3K citations · Full text

Nalp3 Inflammasome, Aluminum Salts, Membrane Biology +5

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

Kenichi Shimada, Timothy R. Crother, Justin N. Karlin et al. · Immunity · 2012 · 2.1K citations · Full text

Mitochondrial Function, Apoptosis, Molecular Biology +5

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

Raúl Muñoz-Planillo, Peter Kuffa, Giovanny J. Martínez-Colón et al. · Immunity · 2013 · 2.1K citations · Full text

Inflammation, Microbial Toxin, Virulence Factor +11

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

Edward A. Miao, Irina A. Leaf, Piper M. Treuting et al. · Nature Immunology · 2010 · 1.3K citations · Full text

Inflammation, Virulence Factor, Apoptosis +13