Concepedia

mTOR up-regulation of PFKFB3 is essential for acute myeloid leukemia cell survival

Yonghuai Feng, Liu-Song Wu

Biochemical and Biophysical Research Communications · 2017 · 64 citations · 17 references

DOI

Concepts

References

17

Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell Carcinoma

Gary R. Hudes, Michael A. Carducci, Piotr Tomczak et al. · New England Journal of Medicine · 2007 · 3.6K citations

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mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery

Do‐Hyung Kim, Dos D. Sarbassov, Siraj M. Ali et al. · Cell · 2002 · 3K citations · Full text

, , +14

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

Katrien De Bock, Sandra Schoors, Anna Kuchnio et al. · Cell · 2013 · 1.6K citations · Full text

, , +11

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR

Mehran S. Neshat, Ingo K. Mellinghoff, Chris Tran et al. · Proceedings of the National Academy of Sciences · 2001 · 973 citations

, , +16

Pivotal Role of mTOR Signaling in Hepatocellular Carcinoma

Augusto Villanueva, Derek Y. Chiang, Pippa Newell et al. · Gastroenterology · 2008 · 728 citations · Full text

, , +17