Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Role of CD47 as a Marker of Self on Red Blood Cells

Per‐Arne Oldenborg, Alex Zheleznyak, Yifu Fang et al. · Science · 2000 · 1.9K citations

Life Sciences, Cell Biology, Immunology +17

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

Ravindra Majeti, Mark P. Chao, Ash A. Alizadeh et al. · Cell · 2009 · 1.7K citations

Medicine, Hematology, Oncology +14

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

Stephen B. Willingham, Jens-Peter Volkmer, Andrew J. Gentles et al. · Proceedings of the National Academy of Sciences · 2012 · 1.7K citations · Full text

Medicine, Immunology, Oncology +17

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

Siddhartha Jaiswal, Catriona Jamieson, Wendy W. Pang et al. · Cell · 2009 · 1.6K citations

Medicine, Cell Biology, Hematology +10