World Journal of Otorhinolaryngology - Head and Neck Surgery · 2016 · 15 citations · 12 references
Veterinary MedicineSurgeryAesthetic SurgeryGeneral SurgeryWound HealingScar ManagementSurgical Wound HealingWound ManagementAnti-inflammatory ResponseCosmetic Outcome AssessmentHoney-based DressingsHoney-based Wound TreatmentsPostoperative Scar Tissue AssessmentScar Outcome MeasurementScar Quality AssessmentScar Topical Therapy
OBJECTIVE: Honey (Manuka honey) has proven to be effective in improving acute and chronic wound healing presumably due to its antibacterial and anti-inflammatory properties. The aim is to determine if Manuka honey decreases scar formation and results in a cosmetically appealing scar. METHODS: A prospective single-blinded randomized control trial was performed. All patients received an 8 cm incision. Patients randomized to honey treatment were instructed to apply Manuka honey paste topically to the incision site once per day post surgery for 4 weeks. The patients' scar was then analyzed objectively by a blinded observer and subjectively at 4 and 8 weeks postoperatively. The primary outcome measure used was the Patient and Observer Scar Assessment Scale (POSAS). RESULTS: A total of 21 patients completed the entire scar analysis (honey treatment = 9, standard treatment = 12). There was no statistically significant difference between patient scar assessment scale and observer scar assessment scale at 4 and 8 weeks postoperatively. CONCLUSION: Honey's reported anti-inflammatory and antibacterial properties, this study did not show a difference in scar appearance when applied.
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Elvira Mavric, Silvia Wittmann, Gerold Barth et al. · Molecular Nutrition & Food Research · 2008 · 624 citations · Full text
Acceleration of wound healing by topical application of honey
Arieh Bergman, Joseph Yanai, Jerry Weiss et al. · The American Journal of Surgery · 1983 · 234 citations