Concepedia

Evaluation of automated Wes system as an analytical and characterization tool to support monoclonal antibody drug product development

Jinyu Wang, Anulfo Valdez, Yingchen Chen

Journal of Pharmaceutical and Biomedical Analysis · 2016 · 28 citations · 12 references

DOI

Concepts

References

12

Monoclonal antibody successes in the clinic

Janice M. Reichert, Clark Rosensweig, Laura Faden et al. · Nature Biotechnology · 2005 · 727 citations

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IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G

Ulrich von Pawel‐Rammingen · The EMBO Journal · 2002 · 481 citations

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Non-enzymatic hinge region fragmentation of antibodies in solution

Armando J. Cordoba, Bao-Jen Shyong, Deirdre Breen et al. · Journal of Chromatography B · 2005 · 186 citations

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β-Elimination and Peptide Bond Hydrolysis:  Two Distinct Mechanisms of Human IgG1 Hinge Fragmentation upon Storage

Steven L. Cohen, Colleen Price, Josef Vlasak · Journal of the American Chemical Society · 2007 · 150 citations

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Characterization of the stability of a fully human monoclonal IgG after prolonged incubation at elevated temperature

Hongcheng Liu, Georgeen Gaza‐Bulseco, Joanne Sun · Journal of Chromatography B · 2006 · 122 citations

, , +11