Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1 - Concepedia

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Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1

DOI Full Paper Access

53

Citations

56

References

2016

Year

Di Shao, Jingyan Han, Xiuyun Hou, Jessica Fry, Jessica B. Behring, Francesca Seta, Michelle T. Long, Hemant K. Roy, Richard A. Cohen, Reiko Matsui,

Antioxidants and Redox Signaling

Abstract

We provide a novel redox-dependent mechanism for regulation of hepatic lipid metabolism, and propose that upregulation of hepatic Glrx may be a beneficial strategy for NAFL. Antioxid. Redox Signal. 27, 313-327.

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