Concepedia

Genome-Wide CRISPR Screen Identifies Regulators of Mitogen-Activated Protein Kinase as Suppressors of Liver Tumors in Mice

Chun‐Qing Song, Yingxiang Li, Haiwei Mou, Jill E. Moore, Angela Park, Yotsawat Pomyen, Soren Hough, Zachary Kennedy, Andrew H. Fischer, Hao Yin,

Gastroenterology · 2016 · 128 citations · 44 references

Open access

Concepts

MedicineGeneticsOncologyCancer GeneticsCarcinogenesisMolecular OncologyCancer GenomicsCrispr-cas SystemsHepatocellular CarcinomaLiver CancerSignal Transduction In CancerTumor Suppressor GenesCrispr InterferenceCrispr RegulationCrispr-cas RegulationGenome-wide Crispr ScreeningMetastatic Liver TumorsMitogen-activated Protein Kinase KinaseMitogen-activated Protein Kinase Signaling

References

44

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Lindsey A. Torre, Freddie Bray, Rebecca L. Siegel et al. · CA A Cancer Journal for Clinicians · 2015 · 27.4K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Ben Langmead, Cole Trapnell, Mihai Pop et al. · Genome biology · 2009 · 23K citations · Full text

Life Sciences, Bioinformatics, High-performance Computing +15

Differential expression analysis for sequence count data

Simon Anders, Wolfgang Huber · Genome biology · 2010 · 16.4K citations · Full text

Life Sciences, Bioinformatics, Biostatistics +15

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations

Life Sciences, Genetics, Molecular Genetics +16

Sorafenib in Advanced Hepatocellular Carcinoma

Josep M. Llovet, Sergio Ricci, Vincenzo Mazzaferro et al. · New England Journal of Medicine · 2008 · 13K citations · Full text

Medicine, Oncology, Pharmacology +12