Concepedia

Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway

Dongqing Jiang, Dianhui Wang, Xianghua Zhuang, Zhanqing Wang, Yihong Ni, Shihong Chen, Fu-dun Sun

Lipids in Health and Disease · 2016 · 62 citations · 18 references

DOIFull text

Open access

Abstract

BBR could increase the expression of ATGL and therefore stimulate basal lipolysis in mature adipocytes through the associated mechanisms related to the AMPK pathway.

References

18

Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

Weijia Kong, Jing Wei, Parveen Abidi et al. · Nature Medicine · 2004 · 1.4K citations

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Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States

Yun Sok Lee, Woo S. Kim, Kang H. Kim et al. · Diabetes · 2006 · 1K citations

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Desnutrin/ATGL Is Regulated by AMPK and Is Required for a Brown Adipose Phenotype

Maryam Ahmadian, Marcia J. Abbott, Tianyi Tang et al. · Cell Metabolism · 2011 · 525 citations · Full text

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Berberine activates thermogenesis in white and brown adipose tissue

Zhiguo Zhang, Huizhi Zhang, Bo Li et al. · Nature Communications · 2014 · 429 citations · Full text

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Adipocyte Lipases and Defect of Lipolysis in Human Obesity

Dominique Langin, Andrea Dicker, Geneviève Tavernier et al. · Diabetes · 2005 · 361 citations · Full text