Influence of a Sub-Therapeutic Level of Virginiamycin in Feed on the Incidence and Persistence of Salmonella typhimurium in Experimentally Infected Swine1

Abstract

Swine were infected with Salmonella typhimurium, USDA #295, and treated with virginiamycin medicated feed continuously at a level of 55 g/metric ton for approximately 2 months. The incidence and persistence of shedding of this organism in the feces and in selected tissues were determined. No significant changes in the course of the infection were detected when virginiamycin treated animals were compared to nonmedicated infected controls.