Trivaric acid, a new inhibitor of PTP1b with potent beneficial effect on diabetes

Global estimates of diabetes prevalence for 2013 and projections for 2035

Leonor Guariguata, David Whiting, Ian Hambleton et al. · Diabetes Research and Clinical Practice · 2013 · 4.6K citations · Full text

Obesity, Diabetes Epidemiology, Global Health +8

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

Konrad Talbot, Hoau-Yan Wang, Hala Kazi et al. · Journal of Clinical Investigation · 2012 · 1.8K citations · Full text

Survival as a function of HbA1c in people with type 2 diabetes: a retrospective cohort study

Craig J. Currie, John R. Peters, Aodán Tynan et al. · The Lancet · 2010 · 875 citations

Metabolic Syndrome, Diabetes Management, Diabetes Epidemiology +5

Crystal Structure of Human Protein Tyrosine Phosphatase 1B

David Barford, Andrew Flint, Nicholas K. Tonks · Science · 1994 · 755 citations

Crystal Structure, Protein Function, Protein Assembly +13

Recent Advances in the Discovery of Competitive Protein Tyrosine Phosphatase 1B Inhibitors for the Treatment of Diabetes, Obesity, and Cancer

Andrew P. Combs · Journal of Medicinal Chemistry · 2009 · 314 citations · Full text

Drug Target, Altmetric Attention Score, Chemical Biology +16