IDH1/2 gene hotspot mutations in central nervous system tumours: analysis of 922 Chinese patients

<i>IDH1</i>and<i>IDH2</i>Mutations in Gliomas

Hai Yan, D. Williams Parsons, Genglin Jin et al. · New England Journal of Medicine · 2009 · 5.9K citations · Full text

Medicine, Genetics, Oncology +16

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

D. Williams Parsons, Siân Jones, Xiaosong Zhang et al. · Science · 2008 · 5.8K citations · Full text

Medicine, Genetics, Oncology +16

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Lenny Dang, David W. White, Bryson D. Bennett et al. · Nature · 2009 · 4.1K citations · Full text

Medicine, Genetics, Molecular Genetics +10

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas

Christian Hartmann, Jochen Meyer, David Capper et al. · Acta Neuropathologica · 2009 · 1.2K citations

Medicine, Molecular Genetics, Pathology +15

Glioma-Derived Mutations in <i>IDH1</i> Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α

Shimin Zhao, Yan Lin, Wei Xu et al. · Science · 2009 · 1.1K citations

Medicine, Molecular Biology, Oncology +17