Concepedia

Development of eosinophilic inflammation is independent of B–T cell interaction in a chronic house dust mite‐driven asthma model

Heleen Vroman, Ingrid M. Bergen, B. W. S. Li, Jennifer A. C. van Hulst, Melanie Lukkes, Denise van Uden, Rudi W. Hendriks, Mirjam Kool

Clinical & Experimental Allergy · 2016 · 29 citations · 33 references

DOI

Abstract

From these findings, we conclude that B-T cell interaction is required for robust Tfh and Th2 cell induction, but not essential for eosinophilic airway inflammation during a chronic HDM-driven asthma model.

References

33

Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen

Maud Plantinga, Martin Guilliams, Manon Vanheerswynghels et al. · Immunity · 2013 · 860 citations · Full text

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A Critical Role for Eosinophils in Allergic Airways Remodeling

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Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity

Juan Moyron‐Quiroz, Javier Rangel‐Moreno, Kim Kusser et al. · Nature Medicine · 2004 · 797 citations

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Mice deficient for the CD40 ligand

Jianchao Xu, Teresa M. Foy, Jon D. Laman et al. · Immunity · 1994 · 735 citations

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PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells

Kim L. Good‐Jacobson, Courtney G Szumilas, Lieping Chen et al. · Nature Immunology · 2010 · 652 citations · Full text

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