Concepedia

Polymer brain-nanotherapeutics for multipronged inhibition of microglial α-synuclein aggregation, activation, and neurotoxicity

Neal K. Bennett, Rebecca Chmielowski, Dalia Abdelhamid, Jonathan J. Faig, Nicola L. Francis, Jean Baum, Zhiping P. Pang, Kathryn E. Uhrich, Prabhas V. Moghe

Biomaterials · 2016 · 27 citations · 68 references

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68

Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

Daniel G. Healy, Mario Falchi, Sean S. O’Sullivan et al. · The Lancet Neurology · 2008 · 1.6K citations · Full text

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CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

Cameron R. Stewart, Lynda M. Stuart, Kim Wilkinson et al. · Nature Immunology · 2009 · 1.5K citations · Full text

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In vivo demonstration that α-synuclein oligomers are toxic

Beate Winner, Roberto Jappelli, Samir K. Maji et al. · Proceedings of the National Academy of Sciences · 2011 · 1.5K citations · Full text

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Aggregated α‐synuclein activates microglia: a process leading to disease progression in Parkinson's disease

Wei Zhang, Tongguang Wang, Zhong Pei et al. · The FASEB Journal · 2005 · 1.3K citations

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Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

Nunilo Cremades, Samuel I. A. Cohen, Emma Deas et al. · Cell · 2012 · 902 citations · Full text

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