PTK7 regulates radioresistance through nuclear factor-kappa B in esophageal squamous cell carcinoma

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

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Medicine, Cancer Biology, Oncology +16

Phase III Trial of Trimodality Therapy With Cisplatin, Fluorouracil, Radiotherapy, and Surgery Compared With Surgery Alone for Esophageal Cancer: CALGB 9781

Joel E. Tepper, Mark J. Krasna, Donna Niedzwiecki et al. · Journal of Clinical Oncology · 2008 · 1.4K citations · Full text

Medicine, Oncology, Surgery +13

The ATM–Chk2–Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Jacob Falck, Niels Mailand, Randi G. Syljuåsen et al. · Nature · 2001 · 1.1K citations

Life Sciences, Cancer Biology, Molecular Biology +12

Progress report of combined chemoradiotherapy versus radiotherapy alone in patients with esophageal cancer: an intergroup study.

Muhyi Al‐Sarraf, Karen Martz, Arnold Herskovic et al. · Journal of Clinical Oncology · 1997 · 744 citations

Medicine, Oncology, Radiation Oncology +14

PI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathways

Peter Graham, Jingli Hao, Jie Ni et al. · Cell Death and Disease · 2014 · 312 citations · Full text

Medicine, Oncology, Pharmacology +17