Concepedia

Plasminogen activator inhibitor type 1 in platelets induces thrombogenicity by increasing thrombolysis resistance under shear stress in an in-vitro flow chamber model

Kazuya Hosokawa, Tomoko Ohnishi‐Wada, Hisayo Sameshima-Kaneko, Tomoka Nagasato, Naoki Miura, Kiyoshi Kikuchi, Takehiko Koide, Ikuro Maruyama, Tetsumei Urano

Thrombosis Research · 2016 · 21 citations · 24 references

DOI

Concepts

References

24

Tissue Plasminogen Activator for Acute Ischemic Stroke

The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group · New England Journal of Medicine · 1995 · 11.7K citations

, , +17

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

Kennedy R. Lees, Erich Bluhmki, Rüdiger von Kummer et al. · The Lancet · 2010 · 2.2K citations

, , +7

Platelets and shear stress

MH Kroll, J. D. Hellums, LV McIntire et al. · Blood · 1996 · 888 citations

, , +12

Platelets synthesize large amounts of active plasminogen activator inhibitor 1

Helén Brogren, Lena Karlsson, Maria Andersson et al. · Blood · 2004 · 206 citations · Full text

, , +8

Plasminogen Activator Inhibitor-1 Is a Major Determinant of Arterial Thrombolysis Resistance

Yanhong Zhu, Peter Carmeliet, William P. Fay · Circulation · 1999 · 183 citations

, , +14