Concepedia

Elevated O-GlcNAcylation of Extracellular Vesicle Proteins Derived from Metastatic Colorectal Cancer Cells.

Parunya Chaiyawat, Churat Weeraphan, Pukkavadee Netsirisawan, Daranee Chokchaichamnankit, Chantragan Srisomsap, Jisnuson Svasti, Voraratt Champattanachai

PubMed · 2017 · 23 citations · 30 references

Abstract

These data, demonstrate that proteins carried by EVs are O-GlcNAc-modified. Importantly, elevated aberrant O-GlcNAcylation of EV proteins might serve as a potential biomarker of metastatic CRC.

References

30

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Jacques Ferlay, Isabelle Soerjomataram, Rajesh Dikshit et al. · International Journal of Cancer · 2014 · 28.8K citations · Full text

Mortality Worldwide, Cancer Management, Epidemiology Of Cancer +17

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

Mariantonia Logozzi, Angelo De Milito, Luana Lugini et al. · PLoS ONE · 2009 · 959 citations · Full text

Cancer Exosomes Trigger Fibroblast to Myofibroblast Differentiation

Jason Webber, Robert Steadman, Malcolm D. Mason et al. · Cancer Research · 2010 · 817 citations · Full text

Extracellular Microvesicles, Cytoskeleton, Cancer Biology +22

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

Jeong-Sun Ju, Rodrigo A. Fuentealba, Sara Miller et al. · The Journal of Cell Biology · 2009 · 484 citations · Full text

Tumor-Derived Microvesicles Induce, Expand and Up-Regulate Biological Activities of Human Regulatory T Cells (Treg)

Marta Szajnik, Malgorzata Czystowska, Mirosław J. Szczepański et al. · PLoS ONE · 2010 · 456 citations · Full text