Concepedia

Two-dimensional Electrophoresis

Two-Dimensional Electrophoresis is a protein separation technique that resolves proteins sequentially in two dimensions—the first based on isoelectric focusing according to charge and the second by molecular weight through SDS-PAGE—thereby enabling high-resolution differentiation of complex protein mixtures.

6.6K

Publications

400K

Citations

24.6K

Authors

3.9K

Institutions

Publications per year

2017–2026

251

Variants

2-De2D Electrophoresis

Parents

Publications

6.6K

High resolution two-dimensional electrophoresis of proteins.

Patrick H. O’Farrell · Journal of Biological Chemistry · 1975 · 19.4K citations · Full text

, , +13

High resolution two-dimensional electrophoresis of basic as well as acidic proteins

Patricia Z. O’Farrell, Howard M. Goodman, Patrick H. O’Farrell · Cell · 1977 · 3.5K citations

, , +12

Ultrasensitive Stain for Proteins in Polyacrylamide Gels Shows Regional Variation in Cerebrospinal Fluid Proteins

Carl R. Merril, David Goldman, S A Sedman et al. · Science · 1981 · 2.9K citations

, , +17

Difference gel electrophoresis. A single gel method for detecting changes in protein extracts

Mustafa Ünlü, Mary E. Morgan, Jonathan S. Minden · Electrophoresis · 1997 · 2.2K citations

, , +14

The current state of two-dimensional electrophoresis with immobilized pH gradients

Angelika Görg, Christian Obermaier, Günther Boguth et al. · Electrophoresis · 2000 · 1.5K citations

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1–5 of 6.6K

Authors

24.6K

  1. DF
    Denis F. Hochstrasser

    University Hospital of Geneva, Switzerland

    35 publications · 4.7K citations

    29

    h-index

  2. PR
    Peter R. Jungblut

    Max Planck Institute for Infection Biology, Germany

    35 publications · 3.4K citations

    29

    h-index

  3. GL
    Gert Lübec

    University of Vienna, Austria

    34 publications · 1.8K citations

    24

    h-index

  4. SH
    Samir Hanash

    University of Michigan, United States

    35 publications · 2.1K citations

    23

    h-index

  5. AG
    Angelika Görg

    Technical University of Munich, Germany

    27 publications · 4K citations

    23

    h-index

1–5 of 24.6K

Institutions

3.9K

  1. Centre National de la Recherche Scientifique

    Paris, France

    50 h-index

    534 publications

    33.7K citations

  2. National Institutes of Health

    Bethesda, United States

    42 h-index

    285 publications

    23.6K citations

  3. University of Michigan

    Ann Arbor, United States

    38 h-index

    275 publications

    18.6K citations

  4. Max Planck Society

    Munich, Germany

    34 h-index

    143 publications

    13.9K citations

  5. Inserm

    Paris, France

    33 h-index

    288 publications

    13.4K citations

  6. National Cancer Institute

    Bethesda, United States

    33 h-index

    180 publications

    16.5K citations

  7. Chinese Academy of Sciences

    Beijing, China

    31 h-index

    280 publications

    17.4K citations

  8. University of California, San Francisco

    San Francisco, United States

    30 h-index

    141 publications

    25.5K citations

1–8 of 3.9K

Venues

  1. Journal of Biological Chemistry

    JBC · 378 publications · 53.9K citations

    101

    h-index

  2. Electrophoresis

    473 publications · 34.8K citations

    94

    h-index

  3. PROTEOMICS

    320 publications · 25.4K citations

    89

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 217 publications · 24.3K citations

    85

    h-index

  5. Journal of Bacteriology

    JB · 161 publications · 11.5K citations

    64

    h-index

1–5