Cathepsin G is broadly expressed in acute myeloid leukemia and is an effective immunotherapeutic target

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

John S. Welch, Timothy J. Ley, Daniel C. Link et al. · Cell · 2012 · 1.6K citations · Full text

Medicine, Genetics, Molecular Genetics +12

An anti–PR1/HLA-A2 T-cell receptor–like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells

Gheath Alatrash, Hong He, Kathryn Ruisaard et al. · Blood · 2011 · 118 citations

Life Sciences, Immunology, Oncology +13

Very low frequencies of human normal CD34⁺ haematopoietic progenitor cells express the Wilms' tumour gene WT1 at levels similar to those in leukaemia cells

Naoki Hosen, Yoshiaki Sonoda, Yusuke Oji et al. · British Journal of Haematology · 2002 · 117 citations · Full text

Life Sciences, Cell Biology, Hematology +8

<i>In vitro</i> Induction of Myeloid Leukemia–Specific CD4 and CD8 T Cells by CD40 Ligand – Activated B Cells Gene Modified to Express Primary Granule Proteins

Hiroshi Fujiwara, J. Joseph Melenhorst, Frank El Ouriaghli et al. · Clinical Cancer Research · 2005 · 97 citations · Full text

Life Sciences, Biotechnology, Immunology +17

Cathepsin G-mediated enhanced TGF-β signaling promotes angiogenesis via upregulation of VEGF and MCP-1

Thomas J. Wilson, Kalyan C. Nannuru, Mitsuru Futakuchi et al. · Cancer Letters · 2009 · 81 citations

Life Sciences, Biochemistry, Molecular Biology +12