Concepedia

Discovery of novel 5-hydroxy-4-pyridone-3-carboxy acids as potent inhibitors of influenza Cap-dependent endonuclease

Masayoshi Miyagawa, Toshiyuki Akiyama, Minako Mikamiyama-Iwata, Kazunari Hattori, Naoko Kurihara, Yoshiyuki Taoda, Chika Takahashi-Kageyama, Noriyuki Kurose, Hidenori Mikamiyama, Naoyuki Suzuki,

Bioorganic & Medicinal Chemistry Letters · 2016 · 12 citations · 28 references

DOI

Concepts

References

28

The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit

Alexandre Dias, Denis Bouvier, Thibaut Crépin et al. · Nature · 2009 · 748 citations

, , +12

A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription

Stephen J. Plotch, Michèle Bouloy, Ismo Ulmanen et al. · Cell · 1981 · 708 citations

, , +16

Seasonal Influenza in Adults and Children—Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management: Clinical Practice Guidelines of the Infectious Diseases Society of America

Scott A. Harper, John S. Bradley, Janet A. Englund et al. · Clinical Infectious Diseases · 2009 · 651 citations · Full text

, , +17

Surveillance for Neuraminidase Inhibitor Resistance among Human Influenza A and B Viruses Circulating Worldwide from 2004 to 2008

Tiffany G. Sheu, Varough Deyde, Margaret Okomo‐Adhiambo et al. · Antimicrobial Agents and Chemotherapy · 2008 · 484 citations · Full text

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Use of influenza A (H1N1) 2009 monovalent vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009.

PubMed · 2009 · 298 citations

, , +17