Concepedia

Human lysosomal acid lipase inhibitor lalistat impairs Mycobacterium tuberculosis growth by targeting bacterial hydrolases

Johannes Lehmann, Jan Vomacka, Knud Esser, Matthew B. Nodwell, Katharina Kolbe, Patrick C. Rämer, Ulrike Protzer, Norbert Reiling, Stephan A. Sieber

MedChemComm · 2016 · 19 citations · 34 references

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Abstract

Lalistat inhibits growth of<italic>Mycobacterium tuberculosis</italic>in bacterial culture as well as in infected macrophages.

References

34

Global tuberculosis report (2014)

L.A. Gabbasova, E.R. Experts Who · 2014 · 13.2K citations

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A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

Vsevolod V. Rostovtsev, Luke G. Green, Valery V. Fokin et al. · Angewandte Chemie International Edition · 2002 · 11.5K citations

, , +8

Peptidotriazoles on Solid Phase:  [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides

Christian W. Tornøe, Caspar Christensen, Morten Meldal · The Journal of Organic Chemistry · 2002 · 8.5K citations

, , +12

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Stewart T. Cole, Roland Brosch, Julian Parkhill et al. · Nature · 1998 · 7.9K citations · Full text

, , +12

Global Burden of Tuberculosis

Christopher Dye, S Scheele, Vikram Pathania et al. · JAMA · 1999 · 3K citations

, , +17