Concepedia

Involvement of tau phosphorylation in traumatic brain injury patients

W-J. Yang, Wenjia Chen, Lie Chen, Y-J. Guo, J-S. Zeng, G-Y. Li, W-S. Tong

Acta Neurologica Scandinavica · 2016 · 37 citations · 12 references

DOI

Abstract

These data suggest that the enhanced tau protein phosphorylation occurs upon severe neuron injures and may contribute to the pathological structural changes of CNS leading to brain damage of TBI.

References

12

The Epidemiology and Impact of Traumatic Brain Injury

Jean Langlois, Wesley Rutland-Brown, Marlena M. Wald · Journal of Head Trauma Rehabilitation · 2006 · 3.6K citations

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Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation

Fei Liu, Inge Grundke‐Iqbal, Khalid Iqbal et al. · European Journal of Neuroscience · 2005 · 742 citations

Widespread Tau and Amyloid‐Beta Pathology Many Years After a Single Traumatic Brain Injury in Humans

Victoria E. Johnson, William Stewart, Douglas H. Smith · Brain Pathology · 2011 · 615 citations

CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease

Katharina Büerger, Michael Ewers, Tuula Pirttilä et al. · Brain · 2006 · 584 citations

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Initial CSF total tau correlates with 1-year outcome in patients with traumatic brain injury

Martin Öst, Karin Nylén, L. Z. Csajbok et al. · Neurology · 2006 · 317 citations