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Efficient in vivo transfection and safety profile of a CpG-free and codon optimized luciferase plasmid using a cationic lipophosphoramidate in a multiple intravenous administration procedure

Mattias F. Lindberg, Tony Le Gall, Nathalie Carmoy, Mathieu Berchel, Stephen C. Hyde, Deborah R. Gill, Paul-Alain Jaffrès, Pierre Lehn, Tristan Montier

Biomaterials · 2015 · 38 citations · 48 references

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48

A Toll-like receptor recognizes bacterial DNA

Hiroaki Hemmi, Osamu Takeuchi, Taro Kawai et al. · Nature · 2000 · 6.4K citations

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Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

Michaël Weber, Ines Hellmann, Michael Stadler et al. · Nature Genetics · 2007 · 2.3K citations

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In vivo gene transfer via intravenous administration of cationic lipid–protamine–DNA (LPD) complexes

S Li, Leaf Huang · Gene Therapy · 1997 · 473 citations

, , +14

Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery

Yong Liu, Leslie C. Mounkes, H. Denny Liggitt et al. · Nature Biotechnology · 1997 · 404 citations

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Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle

Alan R. Brooks, Richard N. Harkins, Peiyin Wang et al. · The Journal of Gene Medicine · 2004 · 372 citations

, , +16