Inhibiting High-Mobility Group Box 1 (HMGB1) Attenuates Inflammatory Cytokine Expression and Neurological Deficit in Ischemic Brain Injury Following Cardiac Arrest in Rats

Regional Variation in Out-of-Hospital Cardiac Arrest Incidence and Outcome

Graham Nichol · JAMA · 2008 · 2K citations

Medicine, Emergency Medical Services, Emergency Medicine +12

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

Hideyuki Yanai, Tatsuma Ban, Zhichao Wang et al. · Nature · 2009 · 686 citations

Life Sciences, Immunology, Molecular Biology +14

Role of IL-1alpha and IL-1beta in ischemic brain damage.

Hervé Boutin, R.A. LeFeuvre, Reiko Horai et al. · PubMed · 2001 · 480 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Role of IL-1α and IL-1β in Ischemic Brain Damage

Hervé Boutin, R.A. LeFeuvre, Reiko Horai et al. · Journal of Neuroscience · 2001 · 434 citations · Full text

Life Sciences, Neurology, Neuroscience +14

Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood–Brain Barrier From Ischemia-Induced Disruption in Rats

Jiyong Zhang, Hideo Takahashi, Keyue Liu et al. · Stroke · 2011 · 316 citations

Medicine, Neurobiology, Neuroscience +17