DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

Akinori Takaoka, Zhichao Wang, Myoung Kwon Choi, +9

Nature

Molecular ImmunologyInnate Immune SystemImmunologyInnate Immune ResponseCytosolic Dna Sensor +3

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

Hideyuki Yanai, Tatsuma Ban, Zhichao Wang, +15

Nature

Innate Immune SystemImmunologyImmunologic MechanismAutoimmunityInnate Immunity +3

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

Zhichao Wang, Myoung Kwon Choi, Tatsuma Ban, +7

Proceedings of the National Academy of Sciences

Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

Daisuke Kurotaki, Naoki Osato, Akira Nishiyama, +10

Blood

IRF8 inhibits C/EBPα activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils

Daisuke Kurotaki, Michio Yamamoto, Akira Nishiyama, +10

Nature Communications

InflammationMolecular ImmunologySignal TransductionGranulocyteInnate Immune System +11

A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA

Myoung Kwon Choi, Zhichao Wang, Tatsuma Ban, +13

Proceedings of the National Academy of Sciences

Innate Immune SystemImmunologyMolecular BiologySelective ContributionRig-i-like Receptor Pathway +18

Lyn Kinase Suppresses the Transcriptional Activity of IRF5 in the TLR-MyD88 Pathway to Restrain the Development of Autoimmunity

Tatsuma Ban, Go Sato, Akira Nishiyama, +19

Immunity

Genetic and chemical inhibition of IRF5 suppresses pre-existing mouse lupus-like disease

Tatsuma Ban, Masako Kikuchi, Go Sato, +19

Nature Communications

Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs)

Hideyuki Yanai, S. Chiba, Tatsuma Ban, +5

Proceedings of the National Academy of Sciences

High AffinityAdaptive Immune SystemHigh-affinity Hmgb BindingImmunologyInnate Immune System +17

A RUNX–CBFβ-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes

Koichi Murakami, Haruka Sasaki, Akira Nishiyama, +10

Nature Immunology

InflammationCytokineLymphocyte DevelopmentImmune Cell DevelopmentImmune Regulation +7