Genetic polymorphisms of CYP2C8, CYP2C9 and CYP2C19 in Ecuadorian Mestizo and Spaniard populations: a comparative study

A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants

Sung Eun Sim, Carl Risinger, Eleni Aklillu et al. · Clinical Pharmacology & Therapeutics · 2006 · 729 citations

Medicine, Pharmacokinetics, Pharmacology +17

Cytochrome 2C19*17 Allelic Variant, Platelet Aggregation, Bleeding Events, and Stent Thrombosis in Clopidogrel-Treated Patients With Coronary Stent Placement

Dirk Sibbing, Werner Koch, Daniela Gebhard et al. · Circulation · 2010 · 583 citations

Medicine, Cardiology, Pharmacology +17

Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations

Joyce A. Goldstein, Takashi Ishizaki, Kan Chiba et al. · Pharmacogenetics · 1997 · 353 citations

Life Sciences, Genetics, Pharmacology +17

Induction of CYP2C genes in human hepatocytes in primary culture.

Sabine Gerbal‐Chaloin, Jean‐Marc Pascussi, Lydiane Pichard‐Garcia et al. · PubMed · 2001 · 318 citations

Medicine, Biochemistry, Pharmacology +15

Validation of Methods for CYP2C9 Genotyping: Frequencies of Mutant Alleles in a Swedish Population

Ümit Yaşar, Erik Eliasson, Marja-Liisa Dahl et al. · Biochemical and Biophysical Research Communications · 1999 · 252 citations

Life Sciences, Genetics, Molecular Genetics +7