Concepedia

Clopidogrel Markedly Increases Plasma Concentrations of CYP2C8 Substrate Pioglitazone

Matti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi, Janne T. Backman

Drug Metabolism and Disposition · 2016 · 36 citations · 40 references

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40

Drug Metabolism and Disposition

Basic & Clinical Pharmacology & Toxicology · 2014 · 2.5K citations

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SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid

Marja K. Pasanen, Mikko Neuvonen, Pertti J. Neuvonen et al. · Pharmacogenetics and Genomics · 2006 · 464 citations

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SLCO1B1 polymorphism markedly affects the pharmacokinetics of lovastatin acid

Aleksi Tornio, Juha Vakkilainen, Mikko Neuvonen et al. · Pharmacogenetics and Genomics · 2015 · 408 citations

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Gemfibrozil and Its Glucuronide Inhibit the Organic Anion Transporting Polypeptide 2 (OATP2/OATP1B1:SLC21A6)-Mediated Hepatic Uptake and CYP2C8-Mediated Metabolism of Cerivastatin: Analysis of the Mechanism of the Clinically Relevant Drug-Drug Interaction between Cerivastatin and Gemfibrozil

Yoshihisa Shitara, Masaru Hirano, Hitoshi Sato et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 405 citations

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Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole*

Pertti J. Neuvonen, Teemu Kantola, Kari T. Kivistö · Clinical Pharmacology & Therapeutics · 1998 · 403 citations

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