U0126 attenuates ischemia/reperfusion-induced apoptosis and autophagy in myocardium through MEK/ERK/EGR-1 pathway

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Public Health, Maternal Health, Obstetrics +17

Apoptosis in Ischemic and Reperfused Rat Myocardium

Henry Fliss, Deborah A Gattinger · Circulation Research · 1996 · 792 citations

Medicine, Cardiology, Pathology +8

Evidence That Curcumin Suppresses the Growth of Malignant Gliomas in Vitro and in Vivo through Induction of Autophagy: Role of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways

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Life Sciences, Oncology, Pharmacology +17

Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress

Shi-Fang Yan, Tomoyuki Fujita, Jiesheng Lu et al. · Nature Medicine · 2000 · 485 citations

Life Sciences, Cell Biology, Molecular Biology +15

Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor α expression by inducing Elk-1 phosphorylation and Egr-1 expression

Mausumee Guha, Maria A. O’Connell, Rafał Pawliński et al. · Blood · 2001 · 371 citations · Full text

Life Sciences, Biochemistry, Immunology +14