Concepedia

Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress

Shi-Fang Yan, Tomoyuki Fujita, Jiesheng Lu, Kenji Okada, Yu Zou, Nigel Mackman, David J. Pinsky, David M. Stern

Nature Medicine · 2000 · 485 citations · 39 references

Concepts

Life SciencesCell BiologyMolecular BiologyCell SignalingGene ExpressionGene RegulationEndoplasmic Reticulum Stress-induced ApoptosisStress Response GenesStress Signaling PathwaysStress-induced Gene ExpressionStress-responsive Gene RegulationCellular Stress SignalingCellular Stress Signaling PathwaysEndoplasmic Reticulum Stress Response GenesEndoplasmic Reticulum Stress ResponsesIschemic HypoxiaOrthologous Gene FamiliesParalogous Gene Families

References

39

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

David W. M. Leung, George Cachianes, Wun-Jing Kuang et al. · Science · 1989 · 5K citations

Life Sciences, Cell Biology, Molecular Biology +10

Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1

Jo A. Forsythe, Bing‐Hua Jiang, Narayan V. Iyer et al. · Molecular and Cellular Biology · 1996 · 4K citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Tissue Destruction by Neutrophils

New England Journal of Medicine · 1989 · 3.7K citations

Life Sciences, Immunology, Pathology +17

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

Harold F. Dvorak, Lawrence F. Brown, Michael Detmar et al. · PubMed · 1995 · 3.1K citations

Veterinary Medicine, Physiology, Tumor Microenvironment +9

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

Jeffrey Milbrandt · Science · 1987 · 1.2K citations

Life Sciences, Neurobiology, Neuroscience +17