PLoS ONE · 2016 · 26 citations · 14 references
PharmacyPediatricsPharmacologyPediatric Clinical PharmacologyPediatric PharmacotherapyPediatric TherapeuticsIntravenous Drug DeliveryPediatric Antibiotic TherapyHigh-concentration ElectrolytesInfection Risk FactorsInfiltrationLogistic RegressionOdds Ratio ModelingPeripheral Intravenous ExtravasationPeripheral Intravenous TherapyRetrospective Case Study
This retrospective study was aimed to identify risk factors of intravenous (IV) infiltration for hospitalized children. The participants were 1,174 children admitted to a general hospital, who received peripheral intravenous injection therapy at least once, and had complete records. Data were analyzed with frequency and percentage or mean and standard deviation were calculated, and odds ratio (OR) from univariate and multiple logistic regressions. The number and % of infiltrations were 92 and 7.8%, respectively. IV infiltration risk factors were lower limb (OR = 1.72), phenytoin (OR = 11.03), 10% dextrose (OR = 6.55), steroids (OR = 6.21), vancomycin (OR = 4.10), high-concentration electrolytes (OR = 3.49), and ampicillin/sulbactam combination (OR = 3.37). Nurses working at children's hospitals should consider the risk of IV infiltration for children receiving IV infusion therapy and make a preventive effort to identify IV infiltration in high-risk children at an early stage.
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Peripheral Intravenous Infiltration Necrosis
PHILIP YOSOWITZ, David A. Ekland, RICHARD C. SHA et al. · Annals of Surgery · 1975 · 91 citations
Reducing Risk of Harm From Extravasation
Eloise Clark, Barbara K. Giambra, John Hingl et al. · Journal of Infusion Nursing · 2012 · 50 citations