Concepedia

Generation and characterization of RAG2 knockout pigs as animal model for severe combined immunodeficiency

Shunichi Suzuki, Masaki Iwamoto, Michiko Hashimoto, Misae Suzuki, Michiko Nakai, Daiichiro Fuchimoto, Shoichiro Sembon, Tomoko Eguchi-Ogawa, Hirohide Uenishi, Akira Ōnishi

Veterinary Immunology and Immunopathology · 2016 · 66 citations · 35 references

DOI

Concepts

References

35

Genomic responses in mouse models poorly mimic human inflammatory diseases

Junhee Seok, H. Shaw Warren, Alex G. Cuenca et al. · Proceedings of the National Academy of Sciences · 2013 · 3K citations · Full text

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RAG-1-deficient mice have no mature B and T lymphocytes

Peter Mombaerts, John Iacomini, Randall S. Johnson et al. · Cell · 1992 · 2.9K citations

, , +13

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

Yoichi Shinkai · Cell · 1992 · 2.6K citations

, , +14

Human Lymphoid and Myeloid Cell Development in NOD/LtSz- <i>scid IL2R</i> γ <i>null</i> Mice Engrafted with Mobilized Human Hemopoietic Stem Cells,

Leonard D. Shultz, Bonnie Lyons, Lisa Burzenski et al. · The Journal of Immunology · 2005 · 1.7K citations · Full text

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NOD/SCID/γcnull mouse: an excellent recipient mouse model for engraftment of human cells

Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi et al. · Blood · 2002 · 1.5K citations

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