Lipocalin-2 Is a Disease Activity Marker in Inflammatory Bowel Disease Regulated by IL-17A, IL-22, and TNF-α and Modulated by IL23R Genotype Status - Concepedia

Concepedia

Publication | Open Access

Lipocalin-2 Is a Disease Activity Marker in Inflammatory Bowel Disease Regulated by IL-17A, IL-22, and TNF-α and Modulated by IL23R Genotype Status

DOI Full Paper Access

122

Citations

34

References

2015

Year

Johannes Stallhofer, Matthias Friedrich, Astrid Konrad-Zerna, Martin Wetzke, Peter Lohse, Jürgen Glas, Cornelia Tillack‐Schreiber, Fabian Schnitzler, Florian Beigel, Stephan Brand

Inflammatory Bowel Diseases

Abstract

Serum LCN2 proves to be a biomarker of active UC. Lower LCN2 levels in CD patients carrying IBD risk-increasing IL23R variants may result from a restricted upregulation of LCN2 due to an impaired Th17 immune response.

References

	Year	Citations

Page 1