Xanthohumol inhibits the extracellular signal regulated kinase (ERK) signalling pathway and suppresses cell growth of lung adenocarcinoma cells

Cancer chemopreventive activity of Xanthohumol, a natural product derived from hop.

Clarissa Gerhäuser, Axel Alt, Amira M. Gamal‐Eldeen et al. · PubMed · 2002 · 412 citations

Medicine, Oncology, Pharmacology +16

Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines

C. L. Miranda, Jan F. Stevens, Angela Helmrich et al. · Food and Chemical Toxicology · 1999 · 398 citations

Medicine, Oncology, Pharmacology +13

CREB in the Pathophysiology of Cancer: Implications for Targeting Transcription Factors for Cancer Therapy

Kathleen M. Sakamoto, David A. Frank · Clinical Cancer Research · 2009 · 291 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Blocking the Raf/MEK/ERK Pathway Sensitizes Acute Myelogenous Leukemia Cells to Lovastatin-Induced Apoptosis

Jianghong Wu, W. Wei‐Lynn Wong, Fereshteh Khosravi et al. · Cancer Research · 2004 · 224 citations

Life Sciences, Cell Biology, Pharmacology +17

Xanthohumol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells

Emily C. Colgate, Cristobal L. Miranda, Jan F. Stevens et al. · Cancer Letters · 2006 · 185 citations

Life Sciences, Cell Biology, Chemical Biology +6