Concepedia

High-Throughput Screening Using Mass Spectrometry within Drug Discovery

Mattias Rohman, Jonathan Wingfield

Methods in molecular biology · 2016 · 29 citations · 11 references

Concepts

PharmacyMedicinal ChemistryPharmacologyAnalytical ChemistryDrug DiscoveryMass Spectrometric AnalysisHigh-throughput ScreeningMass SpectrometryMass Spectrometry Data AnalysisMass Spectrometry-based ProteomicsPeptide AnalysisSmall-molecule ScreeningHigh-throughput Screening AssaysMass Spectrometric ScreeningMass Spectrometry-based ScreeningMass Spectrometry-based Target IdentificationTandem Mass Spectrometry Screening

References

11

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

Pharmacy, Medicinal Chemistry, Drug Design +16

Burger's Medicinal Chemistry and Drug Discovery

European Journal of Medicinal Chemistry · 1997 · 681 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +11

Mass Spectrometry, Review of the Basics: Ionization

H. Awad, Mona M. Khamis, Anas El‐Aneed · Applied Spectroscopy Reviews · 2014 · 171 citations

Natural Sciences, Chemistry, Analytical Chemistry +12

High Throughput Screening via Mass Spectrometry: A Case Study Using Acetylcholinesterase

Can C. Özbal, William A. LaMarr, John R. Linton et al. · Assay and Drug Development Technologies · 2004 · 80 citations

Pharmacy, Biochemistry, Pharmacology +15

High‐Throughput Mass‐Spectrometry Monitoring for Multisubstrate Enzymes: Determining the Kinetic Parameters and Catalytic Activities of Glycosyltransferases

Min Yang, Melissa Brazier‐Hicks, Robert Edwards et al. · ChemBioChem · 2005 · 61 citations

Life Sciences, Biochemistry, Molecular Biology +16