MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Thomas Lang, Kathrin Klein, Joachim E. Fischer et al. · Pharmacogenetics · 2001 · 569 citations

Medicine, Genetics, Molecular Genetics +17

Hepatic CYP2B6 Expression: Gender and Ethnic Differences and Relationship to CYP2B6 Genotype and CAR (Constitutive Androstane Receptor) Expression

Vishal Lamba, Jatinder K. Lamba, Kazuto Yasuda et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 400 citations

Medicine, Genetics, Pharmacology +16

Regulation of the Human CYP2B6 Gene by the Nuclear Pregnane X Receptor

Bryan Goodwin, Linda B. Moore, Catherine M. Stoltz et al. · Molecular Pharmacology · 2001 · 370 citations

Medicine, Molecular Biology, Pharmacology +16

MicroRNAs Regulate CYP3A4 Expression via Direct and Indirect Targeting

Yu-Zhuo Pan, Wenqing Gao, Ai‐Ming Yu · Drug Metabolism and Disposition · 2009 · 271 citations · Full text

Medicine, Molecular Biology, Molecular Genetics +12

Polymorphic<i>CYP2B6</i>: Molecular Mechanisms and Emerging Clinical Significance

Ulrich M. Zanger, Kathrin Klein, Julia Blievernicht et al. · Pharmacogenomics · 2007 · 259 citations

Medicine, Pharmacokinetics, Pharmacology +15