Concepedia

MicroRNAs Regulate CYP3A4 Expression via Direct and Indirect Targeting

Yu-Zhuo Pan, Wenqing Gao, Ai‐Ming Yu

Drug Metabolism and Disposition · 2009 · 271 citations · 25 references

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References

25

The functions of animal microRNAs

Victor Ambros · Nature · 2004 · 10.8K citations

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The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

J�rgen Lehmann, David D. McKee, M. A. Watson et al. · Journal of Clinical Investigation · 1998 · 1.6K citations · Full text

, , +14

Humanized xenobiotic response in mice expressing nuclear receptor SXR

Wen Xie, Joyce L. Barwick, Michael Downes et al. · Nature · 2000 · 657 citations

, , +12

Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin

Olga Kovalchuk, Jody Filkowski, James Meservy et al. · Molecular Cancer Therapeutics · 2008 · 636 citations · Full text

, , +17

A high-throughput method to monitor the expression of microRNA precursors

Thomas D. Schmittgen · Nucleic Acids Research · 2004 · 483 citations · Full text

, , +13