Concepedia

Cytochrome P450IIIA enzymes in rat liver microsomes: involvement in C3-hydroxylation of diazepam and nordazepam but not N-dealkylation of diazepam and temazepam.

P.E.B. Reilly, Diane Thompson, Steven R. Mason, W. D. Hooper

Molecular Pharmacology · 1990 · 48 citations · 0 references

Concepts

MedicinePharmacologyBiochemical PharmacologyDrug MetabolismMetabolismCytochrome P450 EnzymesCytochrome P450-mediated MetabolismDrug-metabolizing EnzymesEnzyme InductionHepatic Drug MetabolismHepatic MetabolismCytochrome P450 Enzyme ActivityCytochrome P450 MonooxygenasesDealkylation ReactionsHydroxylationHydroxylation ReactionsLiver Microsomal MetabolismMicrosomal Drug MetabolismRat Liver Microsomes