Studies of pancreatic function; a simplified method for the determination of serum lipase, using aqueous tributyrin as substrate, with 100 normal values by this method.

Abstract

Abstract A modification of the serum tributyrinase method, eliminating the use of bile or bile salts, has been developed. The final step in the procedure, the titration of the fatty acid, may be carried out either with phenolphthalein as the indicator or electrometrically. The serum tributyrinase level of one hundred normal subjects has been determined. The range of tributyrinase values for the male subjects was higher than that of the female group. The normal range of serum tributyrinase levels was found to vary from 85 to 205 units.