Excessive synthesis of matrix metalloproteinases in exocrine tissues of NOD mouse models for Sjögren's syndrome. - Concepedia

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Excessive synthesis of matrix metalloproteinases in exocrine tissues of NOD mouse models for Sjögren's syndrome.

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References

1998

Year

Shigeo Yamachika, Nanni Jm, Nguyen Kh, Ludivina Y. Garces, Lowry Jm, Robinson Cp, Jason Brayer, Oxford Ge, da Silveira A, Micah Kerr,

Abstract

These observations suggest that excessive MMP activity is associated with autoimmune Sjögren's syndrome-like disease in NOD mice. However, a possible contribution by increased MMP activity in initiation and progression of this autoimmune disease is yet to be elucidated.