Upregulation of Glutaredoxin-1 Activates Microglia and Promotes Neurodegeneration: Implications for Parkinson's Disease - Concepedia

Concepedia

Publication | Open Access

Upregulation of Glutaredoxin-1 Activates Microglia and Promotes Neurodegeneration: Implications for Parkinson's Disease

DOI Full Paper Access

40

Citations

46

References

2016

Year

Olga Gorelenkova Miller, Jessica B. Behring, Sandra L. Siedlak, Sirui Jiang, Reiko Matsui, Markus Bachschmid, Xiongwei Zhu, John J. Mieyal

Antioxidants and Redox Signaling

Abstract

In vitro and in vivo data suggest Grx1 upregulation promotes neurotoxic neuroinflammation, potentially contributing to PD. Antioxid. Redox Signal. 25, 967-982.

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